Healthcare Whitepaper Part 1: Contract Manufacturing Services and Packager Capabilities

Bottle product launch requires fundamental considerations

Selecting the right contract manufacturing services and packaging partner is essential in the dynamic and increasingly complex healthcare environment, where changes in regulatory requirements and supply chain advancements routinely influence the marketplace.

As mergers, consolidations, and brand-buying continue among pharmaceutical companies and consumer packaged goods brands, customers are looking to CMOs to be experts in research and development, compliance, and go-to-market strategies for new products.

Turnkey solutions and speed-to-market are packaging industry watchwords that often head the checklist for consideration when selecting a supplier. But the breadth of capabilitiesquality assuranceestablished supply chain relationships and a commitment to continuous improvement and innovation are key ingredients to a lasting partnership with your contract manufacturing and packaging partner.

Multi-Pack Solutions’ contract manufacturing and packaging services roots run deep in the healthcare industry. In 1986, the company then known as Span-America entered the business with sales of hospital disposables to American Hospital Supply. The company landed its first consumer product in 1988 and today manufactures and packages a variety of name-brand products for the personal care and healthcare industries, including Class I medical devices such as wet wipes in canisters and single-use packets, and Class II medical devices such as personal lubricants.

From regulatory compliance to market preferences for packaging, a true contract manufacturing and packaging partner will be well-versed in the right technology for personal care, OTC, pharmaceuticals, and Medical Device manufacturing and packaging, and will understand the competitive landscape. This type of insight comes only with years of solid experience and trusted industry relationships.

For example, as an aging population and focus on compliance and safety steers healthcare packaging toward options such as easier-to-open containers and self-heating tubes for one-time use, it is important that your contract manufacturing and packaging partner possess the competencies, registrations, and relationships that make the timely implementation of these trends and transitions possible.

With an overarching commitment to Quality, Multi-Pack Solution is FDA-registered and fully compliant. Multi-Pack Solutions, located in Greenville, South Carolina is also registered with the FDA as a Medical Device and Drug Establishment.

In addition, Multi-Pack Solutions is registered with the EPA and compliant with applicable regulations.

The Greenville, South Carolina location partners with an industry-recognized ISO certification body to maintain registration and certification to ISO 13485 to meet all Medical Device part 2003 directives and regulations. It also houses a validated USP Grade Reverse Osmosis Purified Water System—a unique feature when compared with other contract manufacturing and packaging companies.

A custom-built mixing suite in Greenville gives Multi-Pack Solutions compounding ability for a wide range of personal care, pharmaceutical, OTC, and consumer convenience products. These include products from gels and antibacterial liquids to lotions and creams. Capabilities in the mix room include various tank sizes to accommodate pre-mixes and larger scale batches. Some of the tanks are equipped with an exterior jacket to allow for heating and/or cooling phases for formulas that require it.

The company’s technical expertise and quality directives extend across all three manufacturing facilities, which together handle a variety of manufacturing and packaging capabilities including tubes, bottles, sachets, and single packs.

To streamline the supply chain, Multi-Pack Solutions offers expertise in secondary packaging, which eliminates the need for a different company to provide services such as cartoning, coupon and instruction insertion, glue tipping, bundling, and POP displays.


Successfully launching a new healthcare product requires expert go-to-market packaging solutions. Multi-Pack Solutions’ assortment of capabilities gives it technical expertise in virtually every product delivery format.

In selecting contract manufacturing services and packaging partners, the first consideration is whether the company has the ability to produce and package your product. Form factor capabilities and the knowledge to manage the complexities of each—from dispensing to labeling—is an important first step. For example, a bottle product launch requires fundamental considerations such as:

What will the dispensing system be?

From flip to flat cap, ribbed to smooth, and induction-sealed, a proper opening system must be selected for your product.

What is the product’s flowability?

The viscosity of the product and bottle delivery method must work together for optimum dispensing of the bottle contents.

What is the product’s stability?

It is important to know how your product stands up under a variety of environmental factors such as temperature, humidity, and light. Its shelf life must be evaluated for expiration date validation.

Should the product be sealed?

Depending upon the product, its regulatory requirements, and the end-user, your product may or may not require a seal. Your contract packager must understand

What are the timing requirements?

Access to varying bottle sizes and caps is crucial to meeting lead-time structures.

What type of labeling is desired or required?

From front and back to wraparound and booklet labels, there are several ways to present your brand. Your contract packager should be able to make recommendations that are the best fit for your product.

Finding a contract packager that can provide trusted guidance in answering all of these questions, and one that will provide an honest assessment of whether your product is a good match for a long-term partnership is crucial.


At Multi-Pack Solutions, contract packaging is a science. From the shape, size, and color of a bottle to the type of shipper case that bottle is housed in, Multi-Pack Solutions draws from decades of experience to offer expert direction.

As technology continues to evolve in healthcare packaging, you want to make certain that your contract packager is on top of the latest advancements in materials, packaging methods, and equipment and can offer knowledgeable advice in primary and secondary package design and development with your specific product in mind.

Discovering a versatile contract packager is crucial for brand expansion into multiple formats. As you consider a potential product line extension, partnering with a company adept at handling diverse form factors will yield time and cost savings in the future. Choose a provider with technical expertise and practical proficiencies to optimize your brand’s growth potential.


Confidence in your contract packager begins with its commitment to quality. Specialized skills in compliance programs such as calibration, validation, auditing, equipment maintenance, and quality management systems should be evident. When selecting a contract manufacturer and packager, the quality checklist should include considerations such as the contract packager’s ability to provide updates on regulatory requirements, the ability to react to quality issues and partner with the customer, and evidence of the supplier’s continuous improvement programs for quality, manufacturing, and packaging.

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